Diluents and Negative Controls

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Human Plasma

SeraCare's worldwide procurement and donor database networks ensure a safe, reliable supply of human sera and plasma products, highly customizable to meet your specific requirements.

Normal Human Plasma

Processed Human Plasma (including SeraCon)

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Normal Human Serum

SeraCare Human Serum meets the highest quality standards for use as a base matrix, negative control, or in preparation of a positive control for diagnostic kit production.

Human Serum Off Clot

True Human Serum

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Normal Human Plasma

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Processed Human Plasma (including SeraCon)

SeraCon products are cost-effective human serum substitutes for use as diluent and cell culture media.

SeraCare Basematrix is a fully processed and characterized defibrinated human plasma matrix for preparing your assay controls, calibrators, and reference standards.

Features


Basematrix, 12 x 3.5 mL	Cat No B001-0008
Basematrix diluent is formulated for use with in vitro diagnostic test kits for the detection of HBV DNA, HCV RNA, HIV-1 RNA, Human Parvovirus B19 DNA, HAV RNA, HBsAg, anti-HIV 1/2, anti-HTLV I/II, anti-HBc, and anti-HCV. The product is manufactured from dialyzed, defibrinated human plasma that is negative for HBV DNA, HCV RNA, HIV-1 RNA, Human Parvovirus B19 DNA, and HAV RNA, and non-reactive for HBsAg and anti-HIV-1/2, anti-HCV, anti-HTLV I/II, anti-HBs, and anti-HBc. For research use only. Fill size 12 x 3.5 mL More

Basematrix 53, 1L processed plasma	Cat No 501101
Basematrix 53 is a processed, dialyzed, defibrinated human plasma product derived from plasma collected at FDA-licensed facilities in the US. Detailed Certificate of Analysis provided. For research use only. Fill size 1 Liter More

EDTA Human Plasma	Cat No HB-100
This product is derived from human plasma obtained from FDA-licensed facilities. Patient samples have been tested and found negative for anti-HIV-1/HIV-2, HBsAg, anti-HCV, HCV RNA, Syphilis, and HIV-1 Ag and/or HIV-1 RNA. For research use only. Fill size Price $/mL (sold in units) More

SeraCon I	Cat No 21000
This custom processed human plasma is suitable for diluent as a base matrix in preparing controls, and for cell culture growth media. Defibrinated, pooled plasma, 0.2 μm filtered. Affinity stripping is available. Fill sizes 3 Liters More 1 Liter More

SeraCon II	Cat No 22000
This custom processed human plasma is suitable for diluent as a base matrix in preparing controls, and for cell culture growth media. It contains SeraCon I (defibrinated, pooled plasma, 0.2 μm filtered) dialyzed to approximate a human serum profile. Affinity stripping is available. Fill sizes 3 Liters More 1 Liter More

SeraCon II CD	Cat No 22011
This custom processed human plasma is suitable for diluent as a base matrix in preparing controls, and for cell culture growth media. It contains SeraCon I (defibrinated, pooled plasma, 0.2 μm filtered) dialyzed to approximate a human serum profile, delipidated for clarity/stability, and charcoal stripped. Affinity stripping is available. Fill sizes 3 Liters More 1 Liter More

SeraCon II D	Cat No 22001
This custom processed human plasma is suitable for diluent as a base matrix in preparing controls, and for cell culture growth media. It contains SeraCon I (defibrinated, pooled plasma, 0.2 μm filtered) dialyzed to approximate a human serum profile, and delipidated for clarity/stability. Affinity stripping is available. Fill sizes 3 Liters More 1 Liter More

SeraCon Matribase	Cat No 22009
This is a biological matrix made from human blood fractions designed to have lower than normal values for thyroid and sex hormones and total lipids, resulting in a cleaner background signal and increased clarity, making it easier to process. SeraCon Matribase is produced without the use of delipidating agents or activated charcoal, which have been shown to produce false positive results on some viral antibody tests. Designed as a negative control for in vitro diagnostic applications, it is also suitable for use as a diluent or base matrix. Fill size 1 Liter More

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Human Serum Off Clot

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True Human Serum

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Bulk, OEM, and Custom Products

SeraCare Configures to your Specifications

When you require

•   large quantities
•   specialized packaging
•   custom product configuration

SeraCare will work with you to develop the best solution, and satisfy your needs.

Our facilities are ISO certified and comply with cGMP standards, and we have expertise in virology, serology, immunology, and molecular biology.

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Product Features & Benefits


SeraCare plasma and serum products are

•	supplied as individual units, pooled, delipidized, or custom processed

•	tested negative or non-reactive by FDA-licensed tests for infectious disease analytes anti-HIV-1/HIV-2, HBsAg, anti-HCV, and other selected markers

•	traceable back to the donor, with additional information such as donor age, sex, and geographic information available upon request
	—	paid and volunteer donors are verbally and physically screened in compliance with the highest level of FDA regulations

•	available in quantities ranging from 10 mL to thousands of liters and/or single units
	—	pricing is based upon quantity ordered and information requested
	—	supply agreements and long-term contracts are available

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Product Features & Benefits


	•	Naturally clotted

	•	Obtained from volunteer donors at FDA-registered US blood centers

	•	Excellent lot-to-lot reproducibility

	•	Custom bottling and custom processing options

	•	Certificate of Analysis supplied with each lot, confirming donor units have tested negative or non-reactive for anti-HIV-1/2, anti-HCV, and HBsAg

	•	Complete donor traceability maintained

	•	Donor units can be further certified for non-reactivity in assays for anti-HBc, anti-HTLV-1/2, and RPR

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Product Features & Benefits


	•	Processed plasma customized to your specifications—options include defibrination, delipidation, and more

	•	Visually clear, free of precipitate, virtually free of particulate

	•	Low bio-burden: routinely < 10 colony forming units (CFU) per mL

	•	Salt balanced close to physiological conditions

	•	Custom packaging and processing available, including large lots, gender pre-selection

	•	Donor units may be further certified for nonreactivity in assays for anti-HBc, anti-HTLV-I/II, and Syphilis

	•	Sample sizes are available upon request

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Product Features & Benefits


	•	Naturally clotted

	•	Obtained from volunteer donors at FDA-registered US blood centers

	•	Excellent lot-to-lot reproducibility

	•	Custom bottling and custom processing options

	•	Certificate of Analysis supplied with each lot, confirming donor units have tested negative or non-reactive for anti-HIV-1/2, anti-HCV, and HBsAg

	•	Donor units can be further certified for non-reactivity in assays for anti-HBc, anti-HTLV-1/2, and RPR